Evaluating Solid Tumor CAR T Efficacy with Organ-on-a-Chip Technology

Chimeric antigen receptor (CAR) T-cell therapy holds great promise as a treatment for a variety of human cancers, but successfully adapting this treatment for solid tumors has remained elusive. A major challenge is that conventional 2D cell models are unable to recreate the journey that solid tumor CAR T-cell therapy undergoes in the human body. In this video, see how Emulate Organ-Chips can be used to evaluate the efficacy of CAR T-cell therapies and provide a more comprehensive model that integrates both the recruitment and killing aspects of CAR T function.

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