In this webinar, Emeli Chatterjee, Postdoctoral Researcher at Massachusetts General Hospital, and Ben Swenor, Senior Science Liaison at Emulate, present case studies from three peer-reviewed papers highlighting how Organ-Chips have been used to study cardiorenal syndrome, environmental enteric dysfunction (EED), and immunotherapy safety. View now to learn how Organ-Chips can be used to investigate complex disease mechanisms and evaluate immunotherapy safety.
Case study topics include:
- Cardiorenal Syndrome: Investigating the role of extracellular vesicles from patients with cardiorenal syndrome on renal injury using the Kidney-Chip, offering insights into disease mechanisms and potential therapeutic targets.
- Immuno-oncology Safety: Using the Colon Intestine-Chip and Duodenum Intestine-Chip to evaluate the on-target, off-tumor safety of T-cell bispecific antibodies.
- Environmental enteric dysfunction (EED): Replicating EED disease mechanisms with the Duodenum Intestine-Chip, comparing the effects of malnutrition with healthy vs. patient-derived tissue to uncover novel therapeutic targets.
Read the author Q&A here.