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We have developed Intestine-Chips that model the small intestine and the colon. The fluidic channels of our Intestine-Chip make it possible to culture intestinal cells along with commensal bacteria, recreating a human-relevant microbiome. Our Intestine-Chips can be configured with primary, Caco-2, or induced pluripotent stem cells derived from patients with diseases of the intestine.
The Intestine-Chip emulates the fundamental functions of the human intestine. The chip features human intestinal epithelial cells and intestinal-specific endothelial cells and has been used in a range of applications, including in the study of ulcerative colitis, IBS, Crohn’s, and viral infection.
Modeling Radiation Injury-induced Cell Death and Countermeasure Drug Responses in a Human Gut-on-a-ChipDownload
Development of a Primary Human Small Intestine-on-a-Chip Using Biopsy-derived OrganoidsDownload
Enhanced Utilization of Induced Pluripotent Stem Cell–Derived Human Intestinal Organoids Using Microengineered ChipsDownload
Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In VitroDownload
Human / Healthy / Co-Culture
12 & 24 QTY
Our Intestine-Chip will be made available for early-adopter use as a complete kit that includes everything you need to conduct your research. This kit will include Organ-Chips, cells, reagents, training, and support from our team of experts. For more information about kit options and pricing, contact our team.