Organ Model: Lung
Applications: Immunology & Inflammation
Highlights
This study demonstrates how an organoid-based Lung-on-a-Chip model can be used to investigate ventilator-associated pneumonia (VAP) and the impact of mechanical forces on disease severity. Using the Emulate Alveolus Lung-Chip, researchers recreated key features of the human alveolar microenvironment to evaluate epithelial differentiation, barrier function, and susceptibility to Pseudomonas aeruginosa infection under physiological and injurious stretch conditions.
