In the pharmaceutical industry, there is a need for more human-relevant preclinical models that can enable a mechanistic understanding of human diseases and drug action. Organs-on-Chips can help address this need by recreating in vivo-relevant function and key disease phenotypes in a more physiological microenvironment than conventional cell-based models.
In this webinar, we highlight how Organs-on-Chips technology can be applied across drug development to improve translation to the clinic. Geraldine Hamilton, Emulate co-founder, reviews:
- Challenges in drug development and why there is a need for more predictive models
- How the Liver-Chip can be applied to evaluate mechanistic toxicity
- How organoids and Organ-Chips can work together to create a more human-relevant Intestine model
- How to use our Human Emulation System to conduct Organ-Chip studies