Emulate Community Publications Digest: Fall 2025 Issue

With over 130 publications across 30+ organ models, Emulate Organ-Chips are empowering researchers to make game-changing scientific breakthroughs! Download this digest to easily explore all publications related to your field of research, or to just learn more about how the technology itself is developing.

New this quarter:

    Cervix

    • Human Cervix Chip: A Preclinical Model for Studying the Role of the Cervical Mucosa and Microbiome in Female Reproductive Health
    • Induction of cervical dysfunction associated with preterm birth by IL-1 and dysbiotic microbiome revealed in human endocervix chips

    Colon

    • GABAergic signaling contributes to tumor cell invasion and poor overall survival in colorectal cancer

    Intestine (Jejunum)

    • Porcine intestinal organoids cultured in an organ-on-a-chip microphysiological system

    Liver

    • Rat and dog quad-culture liver chip models: Characterization and use to interrogate a potential flavin-containing monooxygenase-mediated, species-specific toxicity of a histamine receptor antagonist
    • Hepatotoxicity evaluation of cannabidiol, cannabinol, cannabichromene and cannabigerol using a human quad culture liver chip
    • Liver quad culture chip as a model for radiation injury research

    Lung (Airway)

    • Multimodal Histologic and Imaging-based Readouts of Complex in vitro Models for Research and Drug Discovery
    • Assessment of drug permeability using a small airway microphysiological system
    • Inflammation and epithelial–mesenchymal transition in a CFTR-depleted human bronchial epithelial cell line revealed by proteomics and human organ-on-a-chip

    Lung (Alveolus)

    • Preclinical assessment of pan-influenza A virus CRISPR RNA therapeutics in a human lung alveolus chip