Discover a new standard in Organ-on-a-Chip technology with the Emulate Chip-R1™ Rigid Chip. This new Organ-Chip consumable is designed to minimize drug absorption for enhanced precision in drug toxicology, ADME, and efficacy studies. The Chip-R1 maintains the two-channel architecture of the Chip-S1® Stretchable Chip while incorporating several enhancements, including low-absorbing rigid materials, increased maximum shear stress in the vascular channel, a tissue-culture treated membrane for streamlined workflows, and a reduced chip membrane pore diameter.
Watch our expert speakers as they dive into the advanced features of the Chip-R1 and share data from our Liver-Chip R1 Application Note, demonstrating how this consumable can be used to model the liver sinusoid and improve prediction of drug-induced liver injury (DILI).
In this webinar, you will:
- Discover the advanced features of the Chip-R1, including its low-absorbing materials, pre-activated tissue culture membrane, and increased maximum vascular channel shear force.
- See how low-drug-absorbing materials reduce compound loss, enabling more precise toxicity and efficacy assessments for lipophilic small molecules.
- Explore the Liver-Chip R1’s robust liver functionality, including albumin production, metabolic activity, and immunofluorescence imaging of the four primary cell types of the human liver sinusoid.
- Learn how to leverage the Liver-Chip R1 for improved DILI detection, with comparative data highlighting the advantages of Liver-Chip R1 over Liver-Chip S1.