Synopsis
Join us on Tuesday, May 27th at 11:30AM EDT (8:30AM PDT / 4:30PM BST / 5:30PM CEST), where Dr. Clive Svendsen from Cedars-Sinai will discuss how Organ-on-a-Chip technology is enabling more physiological models of neurodegeneration to be built. Using iPSC technology to generate chips with neural tissue and a BBB-like barrier, Dr. Svendsen will discuss how these models could be used to develop novel personalized clinical trials or “clinical trial on a chip”.
In this webinar, Dr. Svendsen will summarize three different studies that demonstrate how his lab generated Organ-Chip models for ALS, Parkinson’s disease, and frontotemporal dementia (FTD), and how these models may be used in the future to predict pathology in these disorders and allow interactive studies to predict drug effects. Lastly, Dr. Svendsen will discuss how combining iPSC-based Organ-Chip models with new single cell technology (both transcriptomic and proteomic) will also provide a new way to see exactly how specific drugs interact with different cell types within the chip.
