The Organ-on-a-Chip Technology Blog

Emulate Blog

Cell Central

A blog dedicated to next-generation in vitro models

January 16, 2025 | Community Research

10 Organ-Chip Publications That Defined 2024

2024 was filled with groundbreaking discoveries that showcase the transformative potential of Organ-on-a-Chip technology. From uncovering new disease mechanisms to advancing drug safety and efficacy testing, these studies highlight the various way that Organ-Chips are contributing to cutting-edge research.

December 16, 2024 | Drug-Induced Liver Injury

Ocaliva, Azelaprag, and the Continuing Challenge of Drug-Induced Liver Injury: A Call for Human-Relevant Models

In December, two high-profile drug-induced liver injury (DILI) cases involving Azelaprag and Ocaliva were reported in one week, and at least 11 similar incidents have occurred since 2022. Learn how incorporating predictive, human-relevant models like Organ-Chips could improve drug safety and help to avoid DILI failures.

December 9, 2024 | organ-on-a-chip technology

The Role of Complex In Vitro Models in IND Submissions to the FDA

The pharmaceutical and biotechnology industries are increasingly relying on complex in vitro models (CIVMs) to improve the predictability of preclinical studies. Read this blog to learn what these models are and how they’re powering the next generation of investigational new drug (IND) submissions.