Application Note Testing Transduction of AAV-Based Therapeutics on the Liver-Chip

Testing Transduction of AAV-Based Therapeutics on the Liver-Chip

Overview

In this Liver adeno-associated virus (AAV) transduction Application Note, learn how researchers can test the delivery efficiency and safety of AAV vectors using the Emulate Liver-Chip.

Key highlights:

  • Assess time- and concentration-dependent AAV transduction efficiency  
  • Discriminate between the transduction efficiencies of different AAVs  
  • Evaluate the toxicities of AAV-based gene therapy vectors  
  • Study AAV transport from vasculature to target epithelial tissue in a proof-of-concept study