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Off to Austin for AAAS

February 14, 2018

By Geraldine A. Hamilton, PhD President and Chief Scientific Officer
By Geraldine A. Hamilton, PhD President and Chief Scientific Officer

Off to Austin for AAAS

February 14, 2018

I am honored to be giving a talk with some of our collaborators at the annual meeting of the American Association for the Advancement of Science in Austin, Texas, on February 17. The meeting is one of the world’s largest gatherings of scientists.

The symposium we’ve convened addresses the ways Organs-on-Chips technology is being used for drug development by pharmaceutical companies and for precision medicine by clinicians.

I will give a talk along with Dr. Robert Urban of our collaborator Johnson & Johnson and Dr. Clive Svendsen of Cedars-Sinai.

One of the pioneers in the field of Organs-on-Chips technology, Prof. Dongeun (Dan) Huh of the University of Pennsylvania, will moderate the panel, which is titled, “Emulating Human Biology: Organ-Chips for Drug Development and Personalized Medicine.”

Scientific Session

In my presentation, I will discuss our Organs-on-Chips technology and how it can be used by the pharmaceutical industry to develop drugs that respond to the biology of individuals.

Dr. Robert Urban of Johnson & Johnson will address how Organ-Chips are being used by the pharmaceutical industry today and the potential the technology holds to change the drug development process and reduce the use of animals in research.

Dr. Clive Svendsen of Cedars-Sinai will discuss a precision medicine program that uses patient cells to gain insights about intestinal diseases that have a strong genetic component. This initiative combines the expertise of the Regenerative Medicine Institute at Cedars-Sinai with our Organs-on-Chips technology.

If you’ll be in Austin for the AAAS conference, I hope you will attend this event, which will begin at 10:00 a.m. on Saturday, February 17, 2018, in Ballroom G. Please see below for more details.

Our scientific session will demonstrate how Organ-Chips are advancing research in drug development and in the clinic

Event Synopsis

Emulating Human Biology: Organ-Chips for Drug Development and Personalized Medicine

Organ-Chips are micro-engineered systems that recreate living human biology and are being used in scientific research to recreate human-relevant biology. Blood, air, and nutrient media can be flown through the chips, and mechanical forces can be applied to them, recreating the microenvironment and dynamic state that cells experience inside the body. By introducing organ-specific cells, researchers can emulate different organs, such as the lung, liver, intestine, or brain.

While Organ-Chips were first developed in an academic setting, a collaborative ecosystem of researchers spanning the pharmaceutical industry, regulatory agencies, research hospitals, and universities are now developing and qualifying the technology for a broad range of applications. This innovation holds the potential to change the way we develop medicines, foods, and chemicals. What is potentially even more revolutionary is how cells from an individual patient can be seeded into the chips, opening up new possibilities for personalized medicine.

This panel addresses questions including: how can organ chips help us better understand the fundamentals of human biology and disease? How can they be used to more accurately test the safety and efficacy of medicines, foods, and products? How can this innovation lead to development of new therapeutics?

Moderator

Prof. Dongeun (Dan) Huh of the University of Pennsylvania will give an overview of Organ-Chips and a history of the development of the technology.

Speakers

Dr. Geraldine Hamilton, Emulate Inc., Boston, MA

You-on-a-Chip: Understanding Human Biology and Advancing Personalized Medicine

Dr. Robert Urban, Johnson & Johnson Innovation, Cambridge, MA

Qualifying Organ-Chips as a Human-Relevant Platform to Improve the Drug R&D Process

Dr. Clive Svendsen, Cedars-Sinai Medical Center, Los Angeles, CA

Organ-Chips in the Clinic: A New Way to Determine the Best Treatment for Patients